Trials & Filings

Lilly Depression Treatment Fails Trial

Edivoxetine shows no benefit in MDD when added to SSRI

By: Gil Roth

President, Pharma & Biopharma Outsourcing Association

Eli Lilly and Co. posted results from three studies of edivoxetine. The treatment did not meet the primary study objective of superior efficacy in depression after eight weeks of treatment. When added to a selective serotonin reuptake inhibitor (SSRI), edivoxetine did not separate from placebo on the Montgomery-Asberg Depression Rating Scale (MADRS) in three acute randomized placebo-controlled Phase III studies. While the safety and tolerability of edivoxetine was consistent with previous studi...

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